1. Statement from FDA Commissioner Scott Gottlieb, M.D., on a new qualified health claim for consuming oils with high levels of oleic acid to reduce coronary heart disease risk [FDA], 2018
  2. Guasch-Ferré M., Hu F.B., Martínez-González M.A., Fitó M., Bulló M., Estruch R., Ros E., Corella D., Recondo J., Gómez-Gracia E., et al. Olive oil intake and risk of cardiovascular disease and mortality in the PREDIMED Study. BMC Med. 2014;12:78. doi: 10.1186/1741-7015-12-78.
  3. Martínez-Lapiscina E.H., Clavero P., Toledo E., Estruch R., Salas-Salvadó J., San Julián B., Sanchez-Tainta A., Ros E., Valls-Pedret C., Martinez-Gonzalez M.Á. Mediterranean diet improves cognition: The PREDIMED-NAVARRA randomised trial. J. Neurol. Neurosurg. Psychiatry. 2013;84:1318–1325. doi: 10.1136/jnnp-2012-304792.
  4. Martin-Pelaez S., Castaner O., Sola R., Motilva M.J., Castell M., Perez-Cano F.J., Fito M. (2016, April). Influence of phenol-enriched olive oils on human intestinal immune function. Nutrients 8(4): 213.
  5. Sanchez-Rodriguez E., Biel-Glesson S., Fernandez-Navarro J.R., Calleja M.A., Espejo-Calvo J.A., Gil-Extremera B., de la Torre R., Fito M., Covas M.I., Vilchez P., et al. Effects of virgin olive oils differing their bioactive compound contents on biomarkers of oxidative stress and inflammation in healthy adults: A randomized double-blind controlled trial. Nutrients. 2019;11:561. doi: 10.3390/nu11030561
  6. Fernandes J, Fialho M, Santos R, et al. Is olive oil good for you? A systematic review and meta-analysis on anti-inflammatory benefits from regular dietary intake. Nutrition. 2020;69:110559. doi:10.1016/j.nut.2019.110559
  7. Cho S, Choi CW, Lee DH, et al. High-dose squalene ingestion increases type I procollagen and decreases ultraviolet-induced DNA damage in human skin in vivo but is associated with transient adverse effects. Clin Exp Dermatol. 2009;34(4):500-508. doi:10.1111/j.1365-2230.2008.03133.x
  8. Ramos CI, Andrade de Lima AF, Grilli DG, Cuppari L. The short-term effects of olive oil and flaxseed oil for the treatment of constipation in hemodialysis patients. J Ren Nutr. 2015;25(1):50-56. doi:10.1053/j.jrn.2014.07.009
  9. Mattson FH, Grundy SM, Crouse JR. Optimizing the effect of plant sterols on cholesterol absorption in man. Am J Clin Nutr. 1982;35:697–700.
  10. Heinemann T, Kullak-Ublick GA, Pietruck B, et al. Mechanisms of action of plant sterols on inhibition of cholesterol absorption. Comparison of sitosterol and sitostanol. Eur J Clin Pharmacol. 1991;40(suppl 1):S59–S63.
  11. Muhammad, A.,  Muhammad, J., et al. Anti-Alzheimer’s Studies on β-Sitosterol Isolated from Polygonum hydropiper L. Front Pharmacol. 2017; 8: 697. 2017 Oct 6. doi: 10.3389/fphar.2017.00697
  12. Lu, J.,, Zhao, X., Xu, J.; The Protective Effect of Dietary Phytosterols on Cancer Risk: A Systematic Meta-Analysis; J Oncol. 2019; 2019: 7479518.2019 Jun 23. doi: 10.1155/2019/7479518; 
  13. Baskar, A., Savarimuthu, I., Paulraj, G., Al Numair, K.; Chemopreventive potential of β-Sitosterol in experimental colon cancer model - an In vitro and In vivo study; BMC Complement Altern Med; 2010; 10:24. doi: 10.1186/1472-6882-10-24
  14. Lewis, ED., Meydani, SN., Wu, D. Regulatory role of vitamin E in the immune system and inflammation
  15. Vlachos, G., Scarmeas, N.; Dietary Interventions in Mild Cognitive Impairment and Dementia; Dialogues Clin Neurosci. 2019 Mar;21(1):69-82. 
  16. Galli, F., Birringer, M., Lorkowski, S., Frank, J., Azzi, A., et al. (2016) Vitamin E: emerging aspects and new directions. Free Radic Biol Med (Submitted)
  17. Newmark, H.L. Squalene, olive oil, and cancer risk: A review and hypothesis. Cancer Epidemiol. Biomark. Prev. 1997, 6, 1101–1103.
  18. Owen RW, Giacosa A, Hull WE, Haubner R, Spiegelhalder B, Bartsch H. The antioxidant/anticancer potential of phenolic compounds isolated from olive oil. Eur J Cancer. 2000;36:1235–1247. doi: 10.1016/S0959-8049(00)00103-9
  19. Karan Agrawal et al. Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial; Journal of Functional Foods 36 (2017) 84–93
  20. Beauchamp GK et al.Oleocanthal: a natural anti-inflammatory compound, Nature. 2005 Sep 1; 437(7055):456.
  21. Ayoub NM, Siddique AB, Ebrahim HY, Mohyeldin MM, El Sayed KA; The olive oil phenolic (-)-oleocanthal modulates estrogen receptor expression in luminal breast cancer in vitro and in vivo and synergizes with tamoxifen treatment; Eur J Pharmacol. 2017 Sep 5;810:100-111. doi: 10.1016/j.ejphar.2017.06.019. Epub 2017 Jun 15.
  22. Marković, AK.,Torić, J.,, Barbarić, M., Brala, CJ., Hydroxytyrosol, Tyrosol and Derivatives and Their Potential Effects on Human HealthMolecules. 2019 May; 24(10): 2001.doi: 10.3390/molecules24102001
  23. Hydroxytyrosol, Tyrosol and Derivatives and Their Potential Effects on Human HealthMolecules. 2019 May; 24(10): 2001.doi: 10.3390/molecules24102001